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A history of pancreatitis or severe gastrointestinal disease (such as gastroparesis) are not formal contraindications but are important precautions that require careful consideration
33 Likewise, subsequent studies have revealed no treatment-related changes in REE or 24-h EE in obese individuals without T2DM after at least 14 weeks of treatment with the GLP-1 receptor agonist exenatide, 34, 35 or in REE in T2DM after 4 weeks of liraglutide treatment (2 weeks on 1.8 mg)
Ozempic is a brand-name, FDA-approved pre-filled pen manufactured by Novo Nordisk at fixed doses (0.25, 0.5, 1.0, and 2.0 mg)
PMID: 20360006
Phase 2 trial results showed 24.2% mean body weight loss at 48 weeks impressive numbers that Phase 3 still needs to confirm
